Amelioration of Dystonic Opisthotonus in Pantothenate Kinase‐Associated Neurodegeneration Syndrome with Absent “Eye‐of‐the‐Tiger” Sign Following Bilateral Pallidal Deep Brain Stimulation
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چکیده
منابع مشابه
Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
BACKGROUND Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability. CASE REPORT We report a case of a 69-year-old male with craniocervical dystonia, manifesting primarily as incapacitating blepharospasm refractory to medical treatments. He underwent bilateral globus pallidus (GP) deep brain stimulation (DBS) w...
متن کاملDeep Brain Stimulation for Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (PKAN) is usually associated with dystonia, which is typically severe and progressive over time. Pallidal stimulation (GPi DBS) has been carried out in selected cases of PKAN with drug-resistant dystonia with variable results. We report a 30-month follow-up study of a 30-year-old woman with PKAN-related dystonia treated with GPi DBS. Postoperativ...
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A 5-year-old child had a medical history of epilepsy and a newly presented mental retardation with a life-threatening dystonic storm. Neuroimagings showed bilateral calcification of the pallidum. Several treatment modalities were performed, but the symptoms showed no significant improvement. The patient was operated on in order to place a deep brain stimulation (DBS) targeting b...
متن کاملDeep brain stimulation suppresses pallidal low frequency activity in patients with phasic dystonic movements.
Deep brain stimulation of the globus pallidus internus alleviates involuntary movements in patients with dystonia. However, the mechanism is still not entirely understood. One hypothesis is that deep brain stimulation suppresses abnormally enhanced synchronized oscillatory activity within the motor cortico-basal ganglia network. Here, we explore deep brain stimulation-induced modulation of path...
متن کاملDystonia in neurodegeneration with brain iron accumulation: outcome of bilateral pallidal stimulation
Neurodegeneration with brain iron accumulation encompasses a heterogeneous group of rare neurodegenerative disorders that are characterized by iron accumulation in the brain. Severe generalized dystonia is frequently a prominent symptom and can be very disabling, causing gait impairment, difficulty with speech and swallowing, pain and respiratory distress. Several case reports and one case seri...
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ژورنال
عنوان ژورنال: Movement Disorders Clinical Practice
سال: 2019
ISSN: 2330-1619,2330-1619
DOI: 10.1002/mdc3.12748